Llwytho...

Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA

ABSTRACT: G-quadruplexes are non-canonical DNA structures formed by guanine-rich DNA sequences that are implicated in cancer and aging. Understanding how small molecule ligands interact with quadruplexes is essential both to the development of novel anticancer therapeutics and to the design of new q...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Inorg Chem
Prif Awduron: Sabharwal, Navin C., Mendoza, Oscar, Nicoludis, John M., Ruan, Thomas, Mergny, Jean-Louis, Yatsunyk, Liliya A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801998/
https://ncbi.nlm.nih.gov/pubmed/26748794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-015-1325-8
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