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Potential roles for G-quadruplexes in mitochondria

Some DNA or RNA sequences rich in guanine (G) nucleotides can adopt non-canonical conformations known as G-quadruplexes (G4). In the nuclear genome, G4 motifs have been associated with genome instability and gene expression defects, but they are increasingly recognized to be regulatory structures. R...

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Dades bibliogràfiques
Publicat a:Curr Med Chem
Autors principals: Falabella, Micol, Fernandez, Rafael J., Johnson, F. Brad, Kaufman, Brett A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113130/
https://ncbi.nlm.nih.gov/pubmed/29493440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867325666180228165527
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