Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome

The NLRP3 inflammasome promotes the pathogenesis of metabolic, neurodegenerative and infectious diseases. Increasing evidences show that the NLRP3 inflammasome is a promising therapeutic target in inflammatory diseases. Glucosamine is widely used as a dietary supplement to promote the health of cart...

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Vydáno v:Sci Rep
Hlavní autoři: Chiu, Hsiao-Wen, Li, Lan-Hui, Hsieh, Chih-Yu, Rao, Yerra Koteswara, Chen, Fang-Hsin, Chen, Ann, Ka, Shuk-Man, Hua, Kuo-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447579/
https://ncbi.nlm.nih.gov/pubmed/30944389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42130-z
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