Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation

Activation of the Nod-like receptor 3 (NLRP3) inflammasome is important for activation of innate immune responses, but improper and excessive activation can cause inflammatory disease. We previously showed that glycolysis, a metabolic pathway that converts glucose into pyruvate, is essential for NLR...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Lin, Hsin-Chung, Chen, Yu-Jen, Wei, Yau-Huei, Lin, Hsin-An, Chen, Chien-Chou, Liu, Tze-Fan, Hsieh, Yi-Lin, Huang, Kuo-Yang, Lin, Kuan-Hung, Wang, Hsueh-Hsiao, Chen, Lih-Chyang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039150/
https://ncbi.nlm.nih.gov/pubmed/33854503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.630380
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