載入...
Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation
Activation of the NLRP3 inflammasome is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Pyk2 is essential for NLRP3 inflammasome activation. Here we show that the Src-family kinases (SFKs)-Cbl axis plays a pivotal role in su...
Na minha lista:
| 發表在: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6208430/ https://ncbi.nlm.nih.gov/pubmed/30382081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1163-z |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|