Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition

Activation of the nod-like receptor 3 (NLRP3) inflammasomes is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Cbl plays a pivotal role in suppressing NLRP3 inflammasome activation by inhibiting Pyk2-mediated apoptosis-assoc...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Lin, Hsin-Chung, Chen, Yu-Jen, Wei, Yau-Huei, Chuang, Yu-Ting, Hsieh, Su-Heng, Hsieh, Jing-Yu, Hsieh, Yi-Lin, Ojcius, David M., Huang, Kuo-Yang, Chung, I.-Che, Yuan, Sheng-Ning, Chang, Yu-Sun, Chen, Lih-Chyang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404051/
https://ncbi.nlm.nih.gov/pubmed/32707731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145104
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky