Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome

Gouty arthritis results from the generation of uric acid crystals within the joints. These uric acid crystals activate the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome, which is involved in chronic inflammatory diseases, including gouty arthritis. This study identified the po...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cells
Prif Awduron: Hsieh, Chih-Yu, Li, Lan-Hui, Lam, Yulin, Fang, Zhanxiong, Gan, Chin Heng, Rao, Yerra Koteswara, Chiu, Hsiao-Wen, Wong, Wei-Ting, Ju, Tz-Chuen, Chen, Fang-Hsin, Chernikov, Oleg V., Liu, May-Lan, Hsu, Chung-Hua, Hua, Kuo-Feng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072356/
https://ncbi.nlm.nih.gov/pubmed/31979265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020279
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