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Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome

The NLRP3 inflammasome promotes the pathogenesis of metabolic, neurodegenerative and infectious diseases. Increasing evidences show that the NLRP3 inflammasome is a promising therapeutic target in inflammatory diseases. Glucosamine is widely used as a dietary supplement to promote the health of cart...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chiu, Hsiao-Wen, Li, Lan-Hui, Hsieh, Chih-Yu, Rao, Yerra Koteswara, Chen, Fang-Hsin, Chen, Ann, Ka, Shuk-Man, Hua, Kuo-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447579/
https://ncbi.nlm.nih.gov/pubmed/30944389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42130-z
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