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Serine metabolism supports macrophage IL-1β production.
Serine is a substrate for nucleotides, NADPH and glutathione (GSH) synthesis. Previous studies in cancer cells and lymphocytes have shown that serine-dependent one-carbon units are necessary for nucleotide production to support proliferation. Presently, it is unknown whether serine metabolism impact...
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| Veröffentlicht in: | Cell Metab |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6447453/ https://ncbi.nlm.nih.gov/pubmed/30773464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.01.014 |
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