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Futility sustains memory T cells

Memory T cells display a distinct metabolic prolife compared to effector T cells. In this issue, O’Sullivan et al. report that memory T cells activate a “futile cycle” of de novo fatty acid synthesis and concurrent fatty acid oxidation to generate ATP for cell survival.

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Dades bibliogràfiques
Autors principals: Weinberg, Samuel, Chandel, Navdeep S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130331/
https://ncbi.nlm.nih.gov/pubmed/25035944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.06.009
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