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Futility sustains memory T cells
Memory T cells display a distinct metabolic prolife compared to effector T cells. In this issue, O’Sullivan et al. report that memory T cells activate a “futile cycle” of de novo fatty acid synthesis and concurrent fatty acid oxidation to generate ATP for cell survival.
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130331/ https://ncbi.nlm.nih.gov/pubmed/25035944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.06.009 |
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