Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity

Microcystin-LR (MCLR) is a cyanotoxin produced by blue-green algae that causes liver and kidney toxicities. MCLR toxicity is dependent on cellular uptake through the organic anion transporting polypeptide (OATP) transporters. Nonalcoholic fatty liver disease (NAFLD) progresses through multiple stage...

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Gepubliceerd in:Toxicon
Hoofdauteurs: Clarke, John D., Dzierlenga, Anika, Arman, Tarana, Toth, Erica, Li, Hui, Lynch, Katherine D., Tian, Dan-Dan, Goedken, Michael, Paine, Mary F., Cherrington, Nathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447445/
https://ncbi.nlm.nih.gov/pubmed/30849452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2019.03.002
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