Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity

Microcystin-LR (MCLR) is a cyanotoxin produced by blue-green algae that causes liver and kidney toxicities. MCLR toxicity is dependent on cellular uptake through the organic anion transporting polypeptide (OATP) transporters. Nonalcoholic fatty liver disease (NAFLD) progresses through multiple stage...

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Detalhes bibliográficos
Publicado no:Toxicon
Main Authors: Clarke, John D., Dzierlenga, Anika, Arman, Tarana, Toth, Erica, Li, Hui, Lynch, Katherine D., Tian, Dan-Dan, Goedken, Michael, Paine, Mary F., Cherrington, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447445/
https://ncbi.nlm.nih.gov/pubmed/30849452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2019.03.002
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