Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity

Microcystin-LR (MCLR) is a cyanotoxin produced by blue-green algae that causes liver and kidney toxicities. MCLR toxicity is dependent on cellular uptake through the organic anion transporting polypeptide (OATP) transporters. Nonalcoholic fatty liver disease (NAFLD) progresses through multiple stage...

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Vydáno v:Toxicon
Hlavní autoři: Clarke, John D., Dzierlenga, Anika, Arman, Tarana, Toth, Erica, Li, Hui, Lynch, Katherine D., Tian, Dan-Dan, Goedken, Michael, Paine, Mary F., Cherrington, Nathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447445/
https://ncbi.nlm.nih.gov/pubmed/30849452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2019.03.002
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