CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation

Faithful mitotic chromosome segregation is required for the maintenance of genomic stability. We discovered the phosphorylation of histone H2B at serine 6 (H2B S6ph) as a new chromatin modification site and found that this modification occurs during the early mitotic phases at inner centromeres and...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Seibert, Markus, Krüger, Marcus, Watson, Nikolaus A., Sen, Onur, Daum, John R., Slotman, Johan A., Braun, Thomas, Houtsmuller, Adriaan B., Gorbsky, Gary J., Jacob, Ralf, Kracht, Michael, Higgins, Jonathan M.G., Schmitz, M. Lienhard
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446833/
https://ncbi.nlm.nih.gov/pubmed/30765437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201806057
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