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Fine Tuning the Cell Cycle: Activation of the Cdk1 Inhibitory Phosphorylation Pathway during Mitotic Exit

Inactivation of cyclin-dependent kinase (Cdk) 1 promotes exit from mitosis and establishes G1. Proteolysis of cyclin B is the major known mechanism that turns off Cdk1 during mitotic exit. Here, we show that mitotic exit also activates pathways that catalyze inhibitory phosphorylation of Cdk1, a mec...

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Detalhes bibliográficos
Main Authors: Potapova, Tamara A., Daum, John R., Byrd, Kendra S., Gorbsky, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655249/
https://ncbi.nlm.nih.gov/pubmed/19158392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0771
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