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Cdc5-Dependent Asymmetric Localization of Bfa1 Fine-Tunes Timely Mitotic Exit

In budding yeast, the major regulator of the mitotic exit network (MEN) is Tem1, a GTPase, which is inhibited by the GTPase-activating protein (GAP), Bfa1/Bub2. Asymmetric Bfa1 localization to the bud-directed spindle pole body (SPB) during metaphase also controls mitotic exit, but the molecular mec...

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Detalhes bibliográficos
Main Authors: Kim, Junwon, Luo, Guangming, Bahk, Young Yil, Song, Kiwon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257293/
https://ncbi.nlm.nih.gov/pubmed/22253605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002450
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