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Inhibition of Cdc42 during mitotic exit is required for cytokinesis

The role of Cdc42 and its regulation during cytokinesis is not well understood. Using biochemical and imaging approaches in budding yeast, we demonstrate that Cdc42 activation peaks during the G(1)/S transition and during anaphase but drops during mitotic exit and cytokinesis. Cdc5/Polo kinase is an...

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Detalhes bibliográficos
Main Authors: Atkins, Benjamin D., Yoshida, Satoshi, Saito, Koji, Wu, Chi-Fang, Lew, Daniel J., Pellman, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718968/
https://ncbi.nlm.nih.gov/pubmed/23878274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301090
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