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Inhibition of Cdc42 during mitotic exit is required for cytokinesis

The role of Cdc42 and its regulation during cytokinesis is not well understood. Using biochemical and imaging approaches in budding yeast, we demonstrate that Cdc42 activation peaks during the G(1)/S transition and during anaphase but drops during mitotic exit and cytokinesis. Cdc5/Polo kinase is an...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Atkins, Benjamin D., Yoshida, Satoshi, Saito, Koji, Wu, Chi-Fang, Lew, Daniel J., Pellman, David
التنسيق: Artigo
اللغة:Inglês
منشور في: The Rockefeller University Press 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718968/
https://ncbi.nlm.nih.gov/pubmed/23878274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301090
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