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Drosophila Xpd Regulates Cdk7 Localization, Mitotic Kinase Activity, Spindle Dynamics, and Chromosome Segregation

The trimeric CAK complex functions in cell cycle control by phosphorylating and activating Cdks while TFIIH-linked CAK functions in transcription. CAK also associates into a tetramer with Xpd, and our analysis of young Drosophila embryos that do not require transcription now suggests a cell cycle fu...

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Bibliografske podrobnosti
Main Authors: Li, Xiaoming, Urwyler, Olivier, Suter, Beat
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837399/
https://ncbi.nlm.nih.gov/pubmed/20300654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000876
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