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Transient defects of mitotic spindle geometry and chromosome segregation errors

Assembly of a bipolar mitotic spindle is essential to ensure accurate chromosome segregation and prevent aneuploidy, and severe mitotic spindle defects are typically associated with cell death. Recent studies have shown that mitotic spindles with initial geometric defects can undergo specific rearra...

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Bibliographic Details
Main Authors: Silkworth, William T, Cimini, Daniela
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509025/
https://ncbi.nlm.nih.gov/pubmed/22883214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-7-19
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