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Computer simulations predict that chromosome movements and rotations accelerate mitotic spindle assembly without compromising accuracy

The mitotic spindle self-assembles in prometaphase by a combination of centrosomal pathway, in which dynamically unstable microtubules search in space until chromosomes are captured, and a chromosomal pathway, in which microtubules grow from chromosomes and focus to the spindle poles. Quantitative m...

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Detalhes bibliográficos
Main Authors: Paul, Raja, Wollman, Roy, Silkworth, William T., Nardi, Isaac K., Cimini, Daniela, Mogilner, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747184/
https://ncbi.nlm.nih.gov/pubmed/19717443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908261106
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