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Towards a quantitative understanding of mitotic spindle assembly and mechanics

The ‘simple’ view of the mitotic spindle is that it self-assembles as a result of microtubules (MTs) randomly searching for chromosomes, after which the spindle length is maintained by a balance of outward tension exerted by molecular motors on the MTs connecting centrosomes and chromosomes, and com...

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Bibliografiske detaljer
Main Authors: Mogilner, Alex, Craig, Erin
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951465/
https://ncbi.nlm.nih.gov/pubmed/20930139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.062208
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