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Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

Nephron formation continues throughout kidney morphogenesis in both mice and humans. Lineage tracing studies in mice identified a self‐renewing Six2‐expressing nephron progenitor population able to give rise to the full complement of nephrons throughout kidney morphogenesis. To investigate the origi...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Howden, Sara E, Vanslambrouck, Jessica M, Wilson, Sean B, Tan, Ker Sin, Little, Melissa H
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446205/
https://ncbi.nlm.nih.gov/pubmed/30858339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847483
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