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Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

Nephron formation continues throughout kidney morphogenesis in both mice and humans. Lineage tracing studies in mice identified a self‐renewing Six2‐expressing nephron progenitor population able to give rise to the full complement of nephrons throughout kidney morphogenesis. To investigate the origi...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Howden, Sara E, Vanslambrouck, Jessica M, Wilson, Sean B, Tan, Ker Sin, Little, Melissa H
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446205/
https://ncbi.nlm.nih.gov/pubmed/30858339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847483
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