Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk.

During development, distinct progenitors contribute to the nephrons versus the ureteric epithelium of the kidney. Indeed, previous human pluripotent stem cell-derived models of kidney tissue either contain nephrons or pattern specifically to the ureteric epithelium. By re-analysing the transcription...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Howden, Sara E., Wilson, Sean B., Groenewegen, Ella, Starks, Lakshi, Forbes, Thomas A, Tan, Ker Sin, Vanslambrouck, Jessica M., Holloway, Emily M., Chen, Yi-Hsien, Jain, Sanjay, Spence, Jason R., Little, Melissa H.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026527/
https://ncbi.nlm.nih.gov/pubmed/33378647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.12.001
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