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Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

Nephron formation continues throughout kidney morphogenesis in both mice and humans. Lineage tracing studies in mice identified a self‐renewing Six2‐expressing nephron progenitor population able to give rise to the full complement of nephrons throughout kidney morphogenesis. To investigate the origi...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Howden, Sara E, Vanslambrouck, Jessica M, Wilson, Sean B, Tan, Ker Sin, Little, Melissa H
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446205/
https://ncbi.nlm.nih.gov/pubmed/30858339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847483
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