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Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells
BACKGROUND: Sialic acid–binding immunoglobulin-like lectin (Siglec)-8 is a cell-surface protein expressed selectively on human eosinophils, mast cells, and basophils, making it an ideal target for the treatment of diseases involving these cell types. However, the effective delivery of therapeutic ag...
Shranjeno v:
| izdano v: | J Allergy Clin Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445644/ https://ncbi.nlm.nih.gov/pubmed/28734845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.06.028 |
| Oznake: |
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