Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys

Mu-opioid receptor agonists are clinically effective analgesics, but also produce undesirable effects that limit their clinical utility. The nociceptin opioid peptide (NOP) receptor system also modulates nociception, and NOP agonists might be useful adjuncts to enhance the analgesic effects or atten...

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Publicat a:Eur J Pharmacol
Autors principals: Cornelissen, Jeremy C., Steele, Floyd F., Tenney, Rebekah D., Obeng, Samuel, Rice, Kenner C., Zhang, Yan, Banks, Matthew L.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445635/
https://ncbi.nlm.nih.gov/pubmed/30552903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.12.021
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