Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys

Mu-opioid receptor agonists are clinically effective analgesics, but also produce undesirable effects that limit their clinical utility. The nociceptin opioid peptide (NOP) receptor system also modulates nociception, and NOP agonists might be useful adjuncts to enhance the analgesic effects or atten...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Cornelissen, Jeremy C., Steele, Floyd F., Tenney, Rebekah D., Obeng, Samuel, Rice, Kenner C., Zhang, Yan, Banks, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445635/
https://ncbi.nlm.nih.gov/pubmed/30552903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.12.021
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