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Additive and sub-additive antiallodynic interactions between mu-opioid agonists and N-Methyl D-Aspartate antagonists in male rhesus monkeys

Mu-opioid agonists are clinically effective analgesics, but also produce undesirable effects such as sedation and abuse potential that limit their clinical utility. Glutamatergic systems also modulate nociception, and N-Methyl D-Aspartate (NMDA) receptor antagonists have been proposed as one useful...

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Bibliographische Detailangaben
Veröffentlicht in:Behav Pharmacol
Hauptverfasser: Cornelissen, Jeremy C., Steele, Floyd F., Rice, Kenner C., Nicholson, Katherine L., Banks, Matthew L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760441/
https://ncbi.nlm.nih.gov/pubmed/29239974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000336
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