The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys

RATIONALE: The synthetic nonpeptide NOP (nociceptin/orphanin FQ peptide) receptor agonist Ro 64-6198 produces antinociception in rhesus monkeys. In rodents, it has much more variable effects on pain responses, but has response-rate increasing effects on punished operant behavior and decreases drug r...

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Huvudupphovsmän: Podlesnik, Christopher A., Ko, Mei-Chuan, Winger, Gail, Wichmann, Jürgen, Prinssen, Eric P., Woods, James H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108861/
https://ncbi.nlm.nih.gov/pubmed/20852848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2012-7
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