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Comparison of ion transport determinants between a TMEM16 chloride channel and phospholipid scramblase

Two TMEM16 family members, TMEM16A and TMEM16F, have different ion transport properties. Upon activation by intracellular Ca(2+), TMEM16A—a Ca(2+)-activated Cl(−) channel—is more selective for anions than cations, whereas TMEM16F—a phospholipid scramblase—appears to transport both cations and anions...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Gen Physiol
Egile Nagusiak: Nguyen, Dung M., Chen, Louisa S., Yu, Wei-Ping, Chen, Tsung-Yu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445582/
https://ncbi.nlm.nih.gov/pubmed/30670476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812270
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