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Comparison of ion transport determinants between a TMEM16 chloride channel and phospholipid scramblase

Two TMEM16 family members, TMEM16A and TMEM16F, have different ion transport properties. Upon activation by intracellular Ca(2+), TMEM16A—a Ca(2+)-activated Cl(−) channel—is more selective for anions than cations, whereas TMEM16F—a phospholipid scramblase—appears to transport both cations and anions...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Nguyen, Dung M., Chen, Louisa S., Yu, Wei-Ping, Chen, Tsung-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445582/
https://ncbi.nlm.nih.gov/pubmed/30670476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812270
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