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Cobalt ion interaction with TMEM16A calcium-activated chloride channel: Inhibition and potentiation
TMEM16A, a Ca(2+)-sensitive Cl(-) channel, plays key roles in many physiological functions related to Cl(-) transport across lipid membranes. Activation of this channel is mediated via binding intracellular Ca(2+) to the channel with a relatively high apparent affinity, roughly in the sub-μM to low...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7164836/ https://ncbi.nlm.nih.gov/pubmed/32302365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0231812 |
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