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Factors Influencing Meiotic Recombination Revealed by Whole Genome Sequencing of Single Sperm♦
Recombination is critical to meiosis and evolution, yet many aspects of the physical exchange of DNA via crossovers remain poorly understood. We report an approach for single-cell whole-genome DNA sequencing and sequence 217 individual hybrid mouse sperm, providing a kilobase-resolution genome-wide...
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| Publicado no: | Science |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445350/ https://ncbi.nlm.nih.gov/pubmed/30898902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau8861 |
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