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ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
During meiosis, homologous chromosomes pair and recombine, enabling balanced segregation and generating genetic diversity. In many vertebrates, double-strand breaks (DSBs) initiate recombination within hotspots where PRDM9 binds, and deposits H3K4me3 and H3K36me3. However, no protein(s) recognising...
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| Wydane w: | eLife |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
eLife Sciences Publications, Ltd
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494361/ https://ncbi.nlm.nih.gov/pubmed/32744506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53392 |
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