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Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays

Peptidoglycan (PG) is an essential cell wall component that maintains the morphology and viability of nearly all bacteria. Its biosynthesis requires periplasmic transpeptidation reactions which construct peptide cross-linkages between polysaccharide chains to endow mechanical strength. However, trac...

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Dades bibliogràfiques
Publicat a:Nat Chem
Autors principals: Hsu, Yen-Pang, Hall, Edward, Booher, Garrett, Murphy, Brennan, Radkov, Atanas D., Yablonowski, Jacob, Mulcahey, Caitlyn, Alvarez, Laura, Cava, Felipe, Brun, Yves V., Kuru, Erkin, VanNieuwenhze, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444347/
https://ncbi.nlm.nih.gov/pubmed/30804500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0217-x
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