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Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays

Peptidoglycan (PG) is an essential cell wall component that maintains the morphology and viability of nearly all bacteria. Its biosynthesis requires periplasmic transpeptidation reactions which construct peptide cross-linkages between polysaccharide chains to endow mechanical strength. However, trac...

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Vydáno v:Nat Chem
Hlavní autoři: Hsu, Yen-Pang, Hall, Edward, Booher, Garrett, Murphy, Brennan, Radkov, Atanas D., Yablonowski, Jacob, Mulcahey, Caitlyn, Alvarez, Laura, Cava, Felipe, Brun, Yves V., Kuru, Erkin, VanNieuwenhze, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444347/
https://ncbi.nlm.nih.gov/pubmed/30804500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0217-x
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