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Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays

Peptidoglycan (PG) is an essential cell wall component that maintains the morphology and viability of nearly all bacteria. Its biosynthesis requires periplasmic transpeptidation reactions which construct peptide cross-linkages between polysaccharide chains to endow mechanical strength. However, trac...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Hsu, Yen-Pang, Hall, Edward, Booher, Garrett, Murphy, Brennan, Radkov, Atanas D., Yablonowski, Jacob, Mulcahey, Caitlyn, Alvarez, Laura, Cava, Felipe, Brun, Yves V., Kuru, Erkin, VanNieuwenhze, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444347/
https://ncbi.nlm.nih.gov/pubmed/30804500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0217-x
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