Bio-ModelChecker: Using Bounded Constraint Satisfaction to Seamlessly Integrate Observed Behavior With Prior Knowledge of Biological Networks

The in silico study and reverse engineering of regulatory networks has gained in recognition as an insightful tool for the qualitative study of biological mechanisms that underlie a broad range of complex illness. In the creation of reliable network models, the integration of prior mechanistic knowl...

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Vydáno v:Front Bioeng Biotechnol
Hlavní autoři: Sedghamiz, Hooman, Morris, Matthew, Craddock, Travis J. A, Whitley, Darrell, Broderick, Gordon
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Bioengineering and Biotechnology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443719/
https://ncbi.nlm.nih.gov/pubmed/30972331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00048
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