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Inferring Broad Regulatory Biology from Time Course Data: Have We Reached an Upper Bound under Constraints Typical of In Vivo Studies?

There is a growing appreciation for the network biology that regulates the coordinated expression of molecular and cellular markers however questions persist regarding the identifiability of these networks. Here we explore some of the issues relevant to recovering directed regulatory networks from t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vashishtha, Saurabh, Broderick, Gordon, Craddock, Travis J. A., Fletcher, Mary Ann, Klimas, Nancy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435750/
https://ncbi.nlm.nih.gov/pubmed/25984725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127364
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