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Bio-ModelChecker: Using Bounded Constraint Satisfaction to Seamlessly Integrate Observed Behavior With Prior Knowledge of Biological Networks

The in silico study and reverse engineering of regulatory networks has gained in recognition as an insightful tool for the qualitative study of biological mechanisms that underlie a broad range of complex illness. In the creation of reliable network models, the integration of prior mechanistic knowl...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Sedghamiz, Hooman, Morris, Matthew, Craddock, Travis J. A, Whitley, Darrell, Broderick, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443719/
https://ncbi.nlm.nih.gov/pubmed/30972331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00048
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