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Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain
Repeated intravesical PAR4 (protease activated receptor 4) activation elicits persistent bladder pain lasting 5 days after the last treatment. Persistent bladder pain was fully reversed by a systemic HMGB1 (high mobility box 1) inhibitor while a MIF (macrophage migration inhibitory factor) antagonis...
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| Veröffentlicht in: | Neurosci Lett |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443422/ https://ncbi.nlm.nih.gov/pubmed/30708129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.01.046 |
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