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Spinal macrophage migration inhibitory factor and high mobility group box 1 mediate persistent bladder pain

Repeated intravesical PAR4 (protease activated receptor 4) activation elicits persistent bladder pain lasting 5 days after the last treatment. Persistent bladder pain was fully reversed by a systemic HMGB1 (high mobility box 1) inhibitor while a MIF (macrophage migration inhibitory factor) antagonis...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Ma, Fei, Meyer-Siegler, Katherine L., Leng, Lin, Bucala, Richard, Vera, Pedro L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443422/
https://ncbi.nlm.nih.gov/pubmed/30708129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.01.046
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