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Protease activated-receptor 4 activation as a model of persistent bladder pain: Essential role of macrophage migration inhibitory factor and high mobility group box 1

OBJECTIVES: To develop a rodent model of persistent non-inflammatory bladder pain and to test macrophage migration inhibitory factor and high mobility box group 1 as mediators of bladder pain. METHODS: Female C57BL/6 mice received intravesical instillations of protease activated receptor 4 (100 µmol...

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Detalhes bibliográficos
Publicado no:Int J Urol
Main Authors: Ma, Fei, Hunt, David E, Leng, Lin, Bucala, Richard, Meyer-Siegler, Katherine L, Vera, Pedro L
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436093/
https://ncbi.nlm.nih.gov/pubmed/30112848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iju.13778
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