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Gas/Liquid‐Phase Micro‐Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N‐Sulfinylimines

A micro‐flow nucleophilic trifluoromethylation of carbonyl compounds using gaseous fluoroform was developed. This method also allows the first micro‐flow transformation of N‐sulfinylimines into trifluoromethyl amines with excellent diastereoselectivity. To demonstrate the synthetic utility of this m...

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Detaylı Bibliyografya
Yayımlandı:ChemistryOpen
Asıl Yazarlar: Hirano, Kazuki, Gondo, Satoshi, Punna, Nagender, Tokunaga, Etsuko, Shibata, Norio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442697/
https://ncbi.nlm.nih.gov/pubmed/30976483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201800286
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