Aspirin-triggered proresolving mediators stimulate resolution in cancer

Inflammation in the tumor microenvironment is a strong promoter of tumor growth. Substantial epidemiologic evidence suggests that aspirin, which suppresses inflammation, reduces the risk of cancer. The mechanism by which aspirin inhibits cancer has remained unclear, and toxicity has limited its clin...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gilligan, Molly M., Gartung, Allison, Sulciner, Megan L., Norris, Paul C., Sukhatme, Vikas P., Bielenberg, Diane R., Huang, Sui, Kieran, Mark W., Serhan, Charles N., Panigrahy, Dipak
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442621/
https://ncbi.nlm.nih.gov/pubmed/30862734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804000116
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