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Aspirin-triggered proresolving mediators stimulate resolution in cancer

Inflammation in the tumor microenvironment is a strong promoter of tumor growth. Substantial epidemiologic evidence suggests that aspirin, which suppresses inflammation, reduces the risk of cancer. The mechanism by which aspirin inhibits cancer has remained unclear, and toxicity has limited its clin...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Gilligan, Molly M., Gartung, Allison, Sulciner, Megan L., Norris, Paul C., Sukhatme, Vikas P., Bielenberg, Diane R., Huang, Sui, Kieran, Mark W., Serhan, Charles N., Panigrahy, Dipak
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442621/
https://ncbi.nlm.nih.gov/pubmed/30862734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804000116
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