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Aspirin-triggered proresolving mediators stimulate resolution in cancer

Inflammation in the tumor microenvironment is a strong promoter of tumor growth. Substantial epidemiologic evidence suggests that aspirin, which suppresses inflammation, reduces the risk of cancer. The mechanism by which aspirin inhibits cancer has remained unclear, and toxicity has limited its clin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gilligan, Molly M., Gartung, Allison, Sulciner, Megan L., Norris, Paul C., Sukhatme, Vikas P., Bielenberg, Diane R., Huang, Sui, Kieran, Mark W., Serhan, Charles N., Panigrahy, Dipak
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442621/
https://ncbi.nlm.nih.gov/pubmed/30862734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804000116
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