Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin

Colon cancer recurrence after therapy, such as 5-fluorouracil (5-FU), remains a challenge in the clinical setting. Chemotherapy reduces tumor burden by inducing cell death; however, the resulting dead tumor cells, or debris, may paradoxically stimulate angiogenesis, inflammation, and tumor growth. H...

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Udgivet i:FASEB J
Main Authors: Chang, Jaimie, Bhasin, Swati S., Bielenberg, Diane R., Sukhatme, Vikas P., Bhasin, Manoj, Huang, Sui, Kieran, Mark W., Panigrahy, Dipak
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355061/
https://ncbi.nlm.nih.gov/pubmed/29957058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800019RR
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