PPARα Deficiency in Inflammatory Cells Suppresses Tumor Growth

Inflammation in the tumor bed can either promote or inhibit tumor growth. Peroxisome proliferator-activated receptor (PPAR)α is a central transcriptional suppressor of inflammation, and may therefore modulate tumor growth. Here we show that PPARα deficiency in the host leads to overt inflammation th...

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Detalhes bibliográficos
Main Authors: Kaipainen, Arja, Kieran, Mark W., Huang, Sui, Butterfield, Catherine, Bielenberg, Diane, Mostoslavsky, Gustavo, Mulligan, Richard, Folkman, Judah, Panigrahy, Dipak
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800345/
https://ncbi.nlm.nih.gov/pubmed/17327920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000260
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