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Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics

Within the last several years, top-down proteomics has emerged as a high throughput technique for protein and proteoform identification. This technique has the potential to identify and characterize thousands of proteoforms within a single study, but the absence of accurate false discovery rate (FDR...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: LeDuc, Richard D., Fellers, Ryan T., Early, Bryan P., Greer, Joseph B., Shams, Daniel P., Thomas, Paul M., Kelleher, Neil L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442365/
https://ncbi.nlm.nih.gov/pubmed/30647073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000993
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