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Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits

Class C G protein–coupled receptors (GPCRs) are obligatory dimers that are particularly important for neuronal responses to endogenous and environmental stimuli. Ligand recognition through large extracellular domains leads to the reorganization of transmembrane regions to activate G protein signalin...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Park, Jihye, Selvam, Balaji, Sanematsu, Keisuke, Shigemura, Noriatsu, Shukla, Diwakar, Procko, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442050/
https://ncbi.nlm.nih.gov/pubmed/30723160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006173
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